Pelargonium sidoides extract: Indication, Dosage, Side Effect, Precaution

Generic Medicine Info Patient Medicine Information

This information is not country-specific. Please refer to the Indonesia prescribing information.

Generic Medicine Info

Indications and Dosage

Mouth/Throat
Sore throat

Adult: As spray: 4 sprays in the back of the mouth tid.
Child: ≥12 years Same as adult dose.

Oral
Upper respiratory tract symptoms associated with common cold

Adult: As soln: 30 drops or 1.5 mL tid. As syr: 1.5 teaspoon (7.5 mL) tid. As film-coated tab: 1 tab tid. Max treatment duration: 2 weeks. As chewable tab: 1 tab 4-5 times daily.
Child: 6-11 years As soln: 20 drops or 1 mL tid. As syr: 1 teaspoon (5 mL) tid. As chewable tab: 1 tab 2-4 times daily; ≥12 years As soln/film-coated or chewable tab: Same as adult dose.

Renal Impairment

Severe: Contraindicated.

Hepatic Impairment

Severe: Contraindicated.

Contraindications

Severe renal and hepatic impairment.

Special Precautions

Patient with persistent or chronic cough associated with smoking, asthma, chronic bronchitis or emphysema; cough with excessive phlegm, risk of bleeding. Treatment with a cough and cold medicine in children should be considered carefully due to potential risks and limited evidence on efficacy. Pregnancy and lactation.

Adverse Reactions

Gastrointestinal disorders: Gastric pain, heartburn, nausea, diarrhoea.
Skin and subcutaneous tissue disorders: Allergic skin reactions.

Monitoring Parameters

Monitor lasting or worsening symptoms within 7 days or fever that lasts more than 3 days.

Drug Interactions

May increase risk of bleeding with anticoagulants (e.g. warfarin).

Action

Description:
Mechanism of Action: Pelargonium sidoides root extract is a traditional herbal medicine. It antagonises the bacterial adhesion to epithelia which prevents bacterial colonisation and infection in the upper respiratory tract. It also antagonises bacterial and viral adhesion in the tonsil and pharynx surface.
Synonym: south African geranium.

Storage

Store below 30°C.

MIMS Class

Cough & Cold Preparations

References

Anon. Pelargonium. Lexicomp Online. Hudson, Ohio. Wolters Kluwer Clinical Drug Information, Inc. https://online.lexi.com. Accessed 08/08/2018.

DiaCold Tablets (Diapharm GmbH & Co. KG). MHRA. https://products.mhra.gov.uk/. Accessed 04/09/2018.

Kaloba Pelargonium Cough & Cold Relief Syrup (Dr. Willmar Schwabe GmbH & Co KG). MHRA. https://products.mhra.gov.uk/. Accessed 04/09/2018.

Potter’s Pelargonium Cold Relief Drops (Soho Flordis UK Limited). MHRA. https://products.mhra.gov.uk/. Accessed 04/09/2018.

Umcka Coldcare Alcohol-Free Liquid (Schwabe North America, Inc). DailyMed. Source: U.S. National Library of Medicine. https://dailymed.nlm.nih.gov/dailymed/. Accessed 08/08/2018.

Umcka Coldcare Cherry Tablet, Chewable (Schwabe North America, Inc). DailyMed. Source: U.S. National Library of Medicine. https://dailymed.nlm.nih.gov/dailymed/. Accessed 08/08/2018.

Umcka Coldcare Childrens Cherry Syrup (Schwabe North America, Inc). DailyMed. Source: U.S. National Library of Medicine. https://dailymed.nlm.nih.gov/dailymed/. Accessed 08/08/2018.

Umcka Throat Root Spray (Schwabe North America, Inc). DailyMed. Source: U.S. National Library of Medicine. https://dailymed.nlm.nih.gov/dailymed/. Accessed 08/08/2018.

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